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Drug Interactions Monoamine Oxidase Inhibitors Use of Phentermine is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because 56mg the risk of hypertensive crisis, 56mg phentermine. Alcohol Concomitant use of alcohol with Phentermine may result in an adverse drug reaction. Adrenergic Neuron Blocking 56mg Phentermine phentermine decrease the hypotensive phentermine of adrenergic neuron blocking drugs, 56mg phentermine.
A minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese, due to phentermine weight gain that occurs in maternal 56mg during pregnancy. Phentermine has pharmacologic activity similar to amphetamine d- and dll-amphetamine [see Clinical Pharmacology Animal reproduction studies have not been conducted with Phentermine. If this drug is used during pregnancy, 56mg phentermine, or phentermine the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to a fetus.
Nursing Mothers It is not known if Phentermine is excreted in human milk; however, other amphetamines 56mg present in human milk, 56mg phentermine.
Because of the potential for serious adverse reactions in nursing infants, 56mg phentermine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother, 56mg phentermine. 56mg Use 56mg and effectiveness in pediatric patients phentermine not been established.
Because 56mg obesity is a chronic condition requiring long-term treatment, 56mg phentermine, the use of this phentermine, approved for short-term phentermine, is not recommended. Geriatric Use In general, 56mg phentermine, dose selection for an elderly patient phentermine be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, 56mg phentermine, phentermine cardiac function, and of concomitant 56mg or other drug therapy, 56mg phentermine.
This 56mg is known to be substantially excreted by the kidney, 56mg phentermine, 56mg phentermine, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and best viagra prices online may be useful to monitor renal function. Renal Impairment Based on the reported excretion of Phentermine in urine, phentermine increases can be expected in patients with renal impairment [see Clinical Pharmacology Use caution when administering 56mg to patients with renal impairment.
Abuse Phentermine is related chemically and pharmacologically to the amphetamines.
Phentermine/Topiramate (Qsymia) for Chronic Weight Management
Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability phentermine including a drug as part of a weight reduction program, 56mg phentermine.
Dependence Abuse 56mg amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients 56mg have increased the dosage of these drugs to many times than recommended, 56mg phentermine. Abrupt cessation following prolonged high dosage administration phentermine in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, 56mg phentermine, hyperactivity and personality changes, 56mg phentermine.
A severe phentermine of 56mg intoxication is psychosis, often clinically indistinguishable from schizophrenia, 56mg phentermine. Phentermine The least amount feasible should 56mg prescribed or dispensed at one time in order to minimize the possibility of overdosage. Acute Overdosage Manifestations of acute overdosage include restlessness, 56mg phentermine, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, 56mg phentermine, and panic states.
Fatigue and depression usually follow the central stimulation, 56mg phentermine. Cardiovascular effects include arrhythmia, hypertension or hypotension, and phentermine collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Overdosage of pharmacologically similar compounds has resulted in fatal poisoning usually terminates 56mg convulsions and coma.
Management of acute Phentermine hydrochloride intoxication is largely symptomatic and includes phentermine and sedation with a barbiturate, 56mg phentermine.
Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this phentermine. Acidification of the urine increases Phentermine excretion, 56mg phentermine.
Chronic Intoxication Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes.
The most severe 56mg of chronic intoxications is psychosis, 56mg phentermine, often clinically indistinguishable from phentermine. See Drug Abuse 56mg Dependence 9. The structural formula is as follows: Phentermine hydrochloride, an anorectic agent for oral administration, 56mg phentermine, is available as a tablet containing Each tablet contains the following inactive ingredients: Phentermine - Clinical Pharmacology Mechanism of Phentermine Phentermine is a sympathomimetic amine with pharmacologic activity 56mg to the prototype drugs of this class used in obesity, amphetamine d- and dll-amphetamine.
Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics. Pharmacodynamics Typical actions of amphetamines include central nervous system stimulation and 56mg of blood pressure, 56mg phentermine.
Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Pharmacokinetics Following the administration of Phentermine, Phentermine reaches peak concentrations Cmax after 3 to 4.
Phentermine
Drug Interactions In a single-dose study comparing the exposures after oral administration of best phentermine buy combination capsule of 15 mg Phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg Phentermine capsule or a 92 mg topiramate capsule, there is no significant phentermine exposure change in the presence of Cetirizine online uk. Nonclinical Toxicology Carcinogenesis, Mutagenesis, 56mg phentermine, Impairment of Fertility Studies have not been performed with Phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility, 56mg phentermine.
Clinical Studies In relatively short-term clinical trials, adult obese subjects instructed in dietary management and treated with "anorectic" drugs lost more weight on the average than those treated with placebo and diet. The magnitude 56mg increased weight loss of drug-treated patients 56mg placebo-treated patients is only a fraction of a pound a week.
The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in phentermine weeks. The possible origins of the increased weight loss due 56mg the various drug effects are not established, 56mg phentermine. The amount of weight loss associated with the use of an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, phentermine population treated and the diet prescribed.
Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The natural history of 56mg is measured over several years, whereas the studies cited are restricted phentermine a few weeks' duration; thus, the 56mg impact of drug-induced weight loss over that of diet alone must be considered clinically limited, 56mg phentermine.
Dispense in a tight container as defined in the USP, with a child-resistant closure as required. Keep out of the reach of children. Patient Counseling Information Patients must be 56mg that Phentermine hydrochloride is a short-term a few weeks adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity, 56mg phentermine, and that coadministration of Phentermine with other drugs for weight loss is not recommended [see Indications and Usage 1 and Warnings and Precautions 5.
Patients must be instructed on how much Phentermine phentermine take, 56mg phentermine, and when and how to take it [see Phentermine and Administration 2 ]. Advise pregnant women and nursing mothers not to use Phentermine [see Use in Specific Populations 8.
The risks include, 56mg phentermine, but are not limited to: Development of serious valvular heart disease [see Warnings and Precautions 5.