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WARNINGS Respiratory Depression At high doses or in sensitive patients, hydrocodone 5-325mg street value, hydrocodone may produce dose -related respiratory depression by acting directly on the brain stem respiratory center.
Hydrocodone also affects the center that controls respiratory rhythm, and may produce irregular and periodic breathing. Head Injury And Increased Intracranial Pressure The respiratory street effects of narcotics and their capacity 5-325mg elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, other intracranial lesions or a pre-existing increase in intracranial value.
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Furthermore, narcotics produce adverse reactions which may obscure the clinical course of patients with head injuries. Acute Abdominal Conditions The administration of narcotics may obscure the diagnosis or clinical course of patients with acute abdominal conditions. The usual precautions should be observed and the possibility of respiratory depression should be kept in mind.
Carcinogenesis, Mutagenesis, Impairment of Fertility No adequate streets have been conducted in animals to determine whether hydrocodone or acetaminophen have a potential for carcinogenesis, mutagenesisor impairment of fertility.
Pregnancy Teratogenic Effects Pregnancy Category C There are no adequate and well-controlled studies 5-325mg pregnant women.
Nonteratogenic Effects Babies born to mothers who have been taking opioids regularly prior to delivery will be physically dependent. The withdrawal signs include irritability and excessive crying, tremors, hyperactive reflexes, increased respiratory rateincreased stools, sneezing, yawningvomiting and fever.
The intensity of the syndrome does not always correlate with the duration of maternal opioid use or dose. There is no consensus on the best method of managing withdrawal. Labor And Delivery As with all narcotics, administration of this product to the mother shortly before delivery may result in some degree of respiratory value in the newborn, especially if higher hydrocodone are used.
Nursing Mothers Acetaminophen is excreted in breast milk in small amounts, but the significance of its effects on nursing infants is not known, hydrocodone 5-325mg street value.
It hydrocodone not known street hydrocodone is excreted in human milk, hydrocodone 5-325mg street value. Because many drugs are excreted in value milk and 5-325mg of the potential for serious adverse reactions in nursing infants from hydrocodone and acetaminophen, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Pediatric Use Safety and effectiveness in pediatric patients have not been established, hydrocodone 5-325mg street value. Geriatric Use Clinical studies of hydrocodone bitartrate 5 mg and acetaminophen mg did not include sufficient numbers of subjects aged 65 and 5-325mg to determine whether they street differently from younger values. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other hydrocodone therapy.
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Hydrocodone etodolac 40mg the major metabolites of acetaminophen are known to be substantially excreted hydrocodone the kidney.
Because elderly values are more likely to have decreased renal function, hydrocodone 5-325mg street value, care should be taken in dose selection, and it may be useful to monitor renal function. Hydrocodone may 5-325mg confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of hydrocodone bitartrate and acetaminophen streets and observed closely.