Rx cefixime tablets ip 200mg

Bone and Joint infections Drug Interactions 200mg tablet is the combination of Cefixime cephalosporin and Ofloxacin fluoroquinolone and has unique dual mode cefixime action i.

Is cefixime 200 mg antibiotic safe in pregnancy

Both works instantly and synergistically and gives better patient compliance. Cefixime is an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime, rx cefixime tablets ip 200mg. Cefixime is highly stable in the presence of beta-lactamase enzymes. Cefixime is an effective treatment to stop the spread of several bacterial infections.

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It is often used as a treatment for gonorrhea, pharyngitistyphoid fever and tonsillitis. Ofloxacin belongs to fluoroquinolones group of antimicrobials i.

Ofloxacin is used to treat pneumonia and bronchitis caused by H. It is also used in treating skin infections caused by staphylococcus aureus, and streptococcus pyogenes bacteria. Cefixime has been shown to be active against most strains of the Gram-positive organisms. As with other cephalosporins, bactericidal action of diazepam 5mg street value results from inhibition of bacterial cell- wall synthesis.

The peptidoglycan layer is important for cell wall structural integrity. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin binding proteins PBPs. Beta-lactam antibiotics mimic this site and competitively inhibit PBP crosslinking of peptidoglycan. Cefixime is highly stable in the presence of betalactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime.

Ofloxacin is an antibiotic that stops bacteria multiplication by inhibiting the reproduction and repair of their genetic material DNA. Ofloxacin inhibits the enzyme Bacterial DNA gyrase,which nicks double standard DNA introduces negative super coils and then repeals the nicked ends, rx cefixime tablets ip 200mg.

In Gram positive bacteria the tablet target of Ofloxacin action is a cefixime enzymes Topoisomerase. In place of DNA gyrase or Topoisomerase-4 enzyme the mammalian cells passess an Topoisomerase 2which has very low affinity for Ofloxacin, hence less toxicity to the host Cells.

Ofloxacin is used to treat pneumonia and bronchitis caused by Haemophilus influenzae and 200mg pneumoniae. Ofloxacin is used to treat sexually transmitted diseases i. Ofloxacin is often used to treat urinary infections and prostate infections caused by E.

Adverse Effects 200mg of adverse reactions observed in clinical trials were of a mild and transient nature. The tablet commonly seen adverse reactions in clinical trials of the tablet formulation were gastrointestinal and also adverse reaction have been reported for cephalosporin sensitive person and also in some cases somnolence, nasopharyngitis, fatigue, rx cefixime tablets ip 200mg, dry mouth and pharyngitis, and most were mild to moderate in intensity.

Contraindications This tablet is contraindicated in patients with known allergies to the cephalosporin or penicillin or fluoroquinolone antibiotics. Elevated carbamazepine levels have been reported when tablet cefixime administered concomitantly with carbazepine salt and with warfarin and anticoagulants drugs, the prothrombin time is incecreased when this tablet is administered concomitantly. Ofloxacin form chelates with alkaline earth and transition metal cations when administration of with antacids is containing calcium, magnesium, or aluminum, with sucralfate, with divalent or trivalent cations such as iron, or with multivitamins containing zinc.

Elevated serum levels of cyclosporine have been reported with concomitant use of cyclosporine with some other quinolones.