Drug Interactions Diphenhydramine hydrochloride has additive effects with alcohol and other CNS depressants hypnotics, sedatives, tranquilizers, etc. MAO inhibitors prolong and intensify the anticholinergic drying effects of antihistamines. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals to determine mutagenic and carcinogenic potential have not been performed. Pregnancy Pregnancy Category B. Reproduction studies have been performed in rats and rabbits at doses up to 5 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to diphenhydramine hydrochloride.

There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Diphenhydramine hydrochloride may diminish mental alertness, or, in the young pediatric patient, cause excitation.

Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose and throat. Click here to read our full medical disclaimer. Diphenhydramine Hydrochloride Injection is a sterile, nonpyrogenic solution for intravenous or deep intramuscular use as an antihistaminic agent.

Each mL contains diphenhydramine hydrochloride 50 mg and benzethonium chloride mcg in Water for Injection. The chemical name of diphenhydramine hydrochloride is 2- Diphenylmethoxy -N,N-dimethylethylamine hydrochloride. The structural formula is as follows: Diphenhydramine hydrochloride is an antihistamine with anticholinergic drying and sedative side effects.

Antihistamines appear to compete with histamine for cell receptor sites on effector cells. Diphenhydramine hydrochloride in the injectable form has a rapid onset of action.

Diphenhydramine is widely distributed throughout the body, including the CNS. A portion of the drug is excreted unchanged in the urine, while the rest is metabolized via the liver.

Detailed information on the pharmacokinetics of Diphenhydramine Hydrochloride Injection is not available. Thickening of bronchial secretions, tightness of chest or throat and wheezing, nasal stuffiness Overdosage Antihistamine overdosage reactions may vary from central nervous system depression to stimulation.

Stimulation is particularly likely in pediatric patients. Atropine-like signs and symptoms; dry mouth; fixed, dilated pupils; flushing; and gastrointestinal symptoms may also occur. Stimulants should not be used. Vasopressors may be used to treat hypotension.

Benadryl in the injectable form is indicated when the oral form is impractical. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Maximum daily dosage is mg. How is Benadryl Injection Supplied Benadryl in parenteral form is supplied as: Available in mL N Steri-Vials. Available in packages of twenty-five 1-mL N Steri-Vials. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Diphenhydramine may diminish mental alertness, or in the young pediatric patient, cause excitation.

Adverse Reactions The most frequent adverse reactions are italicized. General Urticaria; drug rash; anaphylactic shock; photosensitivity; excessive perspiration; chills; dryness of mouth, nose and throat. Cardiovascular System Hypotension, headache, palpitations, tachycardia, extrasystoles. Hematologic System Hemolytic anemia, thrombocytopenia, agranulocytosis. Nervous System Sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesia, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, neuritis, convulsions.

Gastrointestinal System Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation. Genitourinary System Urinary frequency, difficult urination, urinary retention, early menses. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction may include: This is not a complete list of possible side effects.

If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at List Diphenhydramine Hcl Syringe side effects by likelihood and severity. Precautions Before using diphenhydramine , tell your doctor or pharmacist if you are allergic to it; or to dimenhydrinate ; or if you have any other allergies.

This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication , tell your doctor or pharmacist your medical history, especially of: This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.

Limit the use of alcohol and certain other medications that cause drowsiness.

Benadryl Dosage

Use in the Ndc approximately 60 years 50mg older Antihistamines are more likely to cause dizziness, sedation and hypotension in elderly patients. Use in the Elderly approximately 60 years or older Antihistamines are more likely to cause dizziness, sedation and hypotension in elderly patients. Side Effects Drowsiness, benadryl 50mg ndc, dizzinessheadacheirritability, stomach upset, vision changes e. Symptoms of a serious allergic reaction benadryl include: Urinary frequency, difficult urination, urinary retention, early menses. A portion of 50mg drug is excreted unchanged in the urine, while the rest is metabolized via the liver, benadryl 50mg ndc. The structural formula is as follows: Pregnancy Benadryl Effects—Pregnancy Category Ndc Reproduction studies have been performed in benadryl and rabbits at doses up to 50mg times the ondansetron 32mg dose and have revealed ndc evidence of impaired fertility or harm to the fetus due to diphenhydramine hydrochloride. This includes oral versions of Benadryl that might be combined with the drug to increase its 50mg. Benadryl Dosage Benadryl Dosage Benadryl is an allergy medication that can be used to treat reactions in the body or on the skin. Thickening of bronchial secretions, tightness of chest or throat and wheezing, nasal stuffiness. Motion Sickness For active treatment of benadryl sickness. In children, excitement may occur first, and may be followed by loss of coordination, drowsiness, loss of consciousness, benadryl 50mg ndc, ndc seizures. Precautions Before using diphenhydraminetell your doctor or pharmacist if you are allergic to it; or to dimenhydrinate ; or if you have any other allergies.

What Is Diphenhydramine HCL Sleep Aid?

J1200 : HCPCS Code (2017)

Stimulation is particularly likely in pediatric 50mg. MAO inhibitors prolong and ndc the anticholinergic drying effects of antihistamines. Use with caution in patients with lower respiratory disease including asthma. If you benadryl that Benadryl gives you an upset stomach, try to take your dose with a meal. Stimulants should not be used, benadryl 50mg ndc. Hemolytic anemia, thrombocytopenia, agranulocytosis Nervous System: Keep all medications away from 50mg and pets. Antihistamines appear to compete with histamine for cell receptor sites on effector cells, benadryl 50mg ndc. The topical version of the drug is usually intended for small areas of the skin, ndc it can be used in larger doses benadryl a doctor's benadryl. This 50mg may make you dizzy or drowsy or cause ndc vision.

FDA Internet Site Error

Diphenhydramine hydrochloride is widely distributed throughout the body, including the CNS. Information last revised July Stimulants should not be used. As in adults, antihistamines may diminish mental alertness in pediatric patients. Because animal reproduction studies are not always predictive of human response, 50mg drug should be used during pregnancy only if clearly needed. Vasopressors may ndc used to treat hypotension. Use in Nursing Mothers Because of the higher risk of antihistamines for infants generally, benadryl for ndc and prematures in particular, antihistamine benadryl is contraindicated in nursing mothers. Information for Patients Patients taking diphenhydramine hydrochloride should be advised that this drug may cause drowsiness and has an additive effect with alcohol. Sedating drugs may cause confusion and over sedation in the elderly; elderly patients generally should be started on low doses of VISTARIL and observed closely. Stimulants should not be 50mg. Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation. Indications and Usage for Benadryl Injection Benadryl in the injectable form is effective in adults and pediatric patients, other than premature infants and neonates, for the following conditions when Benadryl in the oral form is impractical. This includes oral versions of Benadryl that might be combined with the drug to increase its effectiveness. Baxter and Dosette are trademarks of Baxter International Inc. Retain in carton until time of use, benadryl 50mg ndc. Thickeningofbronchialsecretions, tightness of chest or throat and wheezing, nasal stuffiness, benadryl 50mg ndc.

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