In individuals who warrant treatment with ivermectin for any reason and have had significant exposure to Loa loa-endemic areas of West or Central Africa, pretreatment assessment for loiasis and careful post-treatment follow-up should be implemented. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals have not been performed to evaluate the carcinogenic potential of ivermectin. Pregnancy, Teratogenic Effects Pregnancy Category C Ivermectin has been shown to be teratogenic in mice, rats, and rabbits when given in repeated doses of 0.
Teratogenicity was characterized in the three species tested by cleft palate ; clubbed forepaws were additionally observed in rabbits. These developmental effects were found only at or near doses that were maternotoxic to the pregnant female. Therefore, ivermectin does not appear to be selectively fetotoxic to the developing fetus.
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Lorraine Shelton breeds and shows under the Featherland cattery name. She has a Persian breeding program specializing in chocolate and lilac, a small Selkirk Rex program, and a blossoming Turkish Angora program. Lorraine is a noted author, geneticist and line-chaser. This article is part of a series of articles she has written on health issues of interest to cat breeders which are published on the Fanciers Health Yahoo Group email list.
I've been getting lots of private requests for information on dosing ivermectin to treat ear mites, body mites and roundworms in cats. What strength of Ivermectin should I use? How much is the dose? I recommend using the 0. The dose is "one drop per pound" 0. One source for purchasing Ivomec 0. Can it be given topically? Animals should be appropriately restrained to achieve the proper route of administration. Inject under the loose skin in front of or behind the shoulder see illustration.
When using the , or mL pack size, use only automatic syringe equipment. Use sterile equipment and sanitize the injection site by applying a suitable disinfectant. Clean, properly disinfected needles should be used to reduce the potential for injection site infections. No special handling or protective clothing is necessary. Inject under the skin, immediately behind the ear see illustration.
When using the mL, mL or mL pack size, use only automatic syringe equipment. As with any injection, sterile equipment should be used. The injection site should be cleaned and disinfected with alcohol before injection. The rubber stopper should also be disinfected with alcohol to prevent contamination of the contents. Mild and transient pain reactions may be seen in some swine following subcutaneous administration.
Recommended Treatment Program Swine: At the time of initiating any parasite control program, it is important to treat all breeding animals in the herd. Treat prior to farrowing, preferably days before, to minimize infection of piglets.
Treat days prior to breeding. Treat days prior to farrowing. Frequency and need for treatments are dependent upon exposure. Treat at least two times a year. Pigs exposed to contaminated soil or pasture may need retreatment if reinfection occurs. However, since the ivermectin effect is not immediate, care must be taken to prevent reinfestation from exposure to untreated animals or contaminated facilities.
Generally, pigs should not be moved to clean quarters or exposed to uninfested pigs for approximately one week after treatment.
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