Talk with the doctor. It may be given to you for other reasons. If you have an allergy to duloxetine or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: Kidney disease or liver disease.
If you are taking thioridazine. If you are taking any of these drugs: Linezolid or methylene blue. If you have taken certain drugs used for low mood depression like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking duloxetine within 14 days of those drugs can cause very bad high blood pressure. This is not a list of all drugs or health problems that interact with this medicine.
Slideshow 21 Arthritis Facts: It's A Game Changer Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. You must check to make sure that it is safe for you to take duloxetine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Duloxetine? Tell all of your health care providers that you take this medicine. Concerning risk factors for suicidality in depression, see above.
Physicians should encourage patients to report any distressing thoughts or feelings at any time. Use in Children and Adolescents Under 18 Years of Age Cymbalta should not be used in the treatment of children and adolescents under the age of 18 years. Suicide-related behaviours suicide attempts and suicidal thoughts and hostility predominantly aggression, oppositional behaviour, and anger were more frequently observed in clinical trials among children and adolescents treated with antidepressants compared to those treated with placebo.
If, based on clinical need, a decision to treat is nevertheless taken, the patient should be carefully monitored for the appearance of suicidal symptoms see section 5. In addition, long-term safety data in children and adolescents concerning growth, maturation, and cognitive and behavioural development are lacking see section 4.
The majority of cases of hyponatraemia were reported in the elderly, especially when coupled with a recent history of, or condition pre-disposing to, altered fluid balance.
Caution is required in patients at increased risk for hyponatraemia, such as elderly, cirrhotic, or dehydrated patients, or patients treated with diuretics. Discontinuation of Treatment Withdrawal symptoms when treatment is discontinued are common, particularly if discontinuation is abrupt see section 4. The risk of withdrawal symptoms seen with SSRIs and SNRIs may be dependent on several factors, including the duration and dose of therapy and the rate of dose reduction.
The most commonly reported reactions are listed in section 4. Generally, these symptoms are mild to moderate; however, in some patients they may be severe in intensity. They usually occur within the first few days of discontinuing treatment, but there have been very rare reports of such symptoms in patients who have inadvertently missed a dose.
Generally, these symptoms are self-limiting and usually resolve within 2 weeks, though in some individuals they may be prolonged months or more. It is therefore advised that duloxetine should be gradually tapered when discontinuing treatment over a period of no less than 2 weeks, according to the patient's needs see section 4.
Elderly Data on the use of Cymbalta mg in elderly patients with major depressive disorder and generalised anxiety disorder are limited. Therefore, caution should be exercised when treating the elderly with the maximum dosage see sections 4.
This is most likely to occur within the first few weeks of treatment. In patients who develop these symptoms, increasing the dose may be detrimental.
Medicinal Products Containing Duloxetine Duloxetine is used under different trademarks in several indications treatment of diabetic neuropathic pain, major depressive disorder, generalised anxiety disorder and stress urinary incontinence. The use of more than one of these products concomitantly should be avoided. Most of them occurred during the first months of treatment. The pattern of liver damage was predominantly hepatocellular. Duloxetine should be used with caution in patients treated with other medicinal products associated with hepatic injury.
Sucrose Cymbalta hard gastro-resistant capsules contain sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency should not take this medicine. There is a separate medicine leaflet called Duloxetine for urinary symptoms which gives more information about duloxetine when it is used for this condition. Before taking duloxetine Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.
For these reasons, before you start taking duloxetine it is important that your doctor knows: If you are pregnant, trying for a baby or breast-feeding. If you have any problems with the way your liver works, or any problems with the way your kidneys work. If you have a heart condition. If you have increased eye pressure called glaucoma.
If you have high blood pressure. If you have ever had 'high' moods, such as mania in bipolar disorder. If you have ever had a fit seizure. If you have a blood disorder that increases your risk of bleeding. If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines. If you have ever had an allergic reaction to a medicine. Depression and other psychiatric illnesses are associated with an increased risk of suicidal thoughts, self-harm, and suicide.
You should be aware that this medicine may not start to make you feel better for at least two to four weeks. However, it is important that you keep taking it in order for it to work properly and for you to feel better. If you feel your depression or anxiety has got worse, or if you have any distressing thoughts or feelings about suicide or harming yourself in these first few weeks, or indeed at any point during treatment or after stopping treatment, then it is very important to talk to your doctor.
This also applies if you are taking this medicine for diabetic nerve pain. Duloxetine has not been studied in children. However, in clinical trials of other antidepressants in children and adolescents, suicide attempts, suicidal thoughts and hostility were more frequently observed in those taking antidepressants compared to those treated with placebo dummy pills. Duloxetine is not licensed and not recommended for any uses in children and adolescents under 18 years of age. However, some specialists may still prescribe it if they feel it is essential.
If your child is prescribed duloxetine you should discuss its safety and potential adverse effects with your child's specialist. For depression and diabetic neuropathic pain: The usual dose of Duloxetine is 60 mg once a day, but your doctor will prescribe the dose that is right for you. For generalised anxiety disorder: The usual starting dose of Duloxetine is 30 mg once a day after which most patients will receive 60 mg once a day, but your doctor will prescribe the dose that is right for you.
The dose may be adjusted up to mg a day based on your response to Duloxetine. To help you remember to take Duloxetine, you may find it easier to take it at the same time every day. Talk with your doctor about how long you should keep taking Duloxetine. Do not stop taking Duloxetine, or change your dose, without talking to your doctor. Treating your disorder properly is important to help you get better.
If it is not treated, your condition may not go away and may become more serious and difficult to treat. If you take more Duloxetine than you should Call your doctor or pharmacist immediately if you take more than the amount of Duloxetine prescribed by your doctor.
Symptoms of overdose include sleepiness, coma, serotonin syndrome a rare reaction which may cause feelings of great happiness, drowsiness, clumsiness, restlessness, feeling of being drunk, fever, sweating or rigid muscles , fits, vomiting and fast heart rate. If you forget to take Duloxetine If you miss a dose, take it as soon as you remember.
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