What other drugs will affect acetaminophen and hydrocodone? Do not take acetaminophen and hydrocodone with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medicines that can make you sleepy or slow your breathing.
Dangerous side effects may result. Tell your doctor about all other medicines you use, especially: This list is not complete and other drugs may interact with acetaminophen and hydrocodone. Tell your doctor about all medications you use.
This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Where can I get more information? Some signs of hydrocodone addiction include taking more than intending to and prioritizing drug use over personal or professional responsibilities. Addictions to hydrocodone, Vicodin, Norco and Lortab can spiral out of control quickly.
Get help for a hydrocodone addiction now. Hydrocodone and Other Drugs Abusing hydrocodone alongside other drugs can increase the likelihood of negative effects or overdose. Mixing hydrocodone with alcohol can be especially dangerous, as both substances are central nervous system depressants.
In some cases, combined hydrocodone and alcohol abuse can lead to respiratory failure. All too often, people who have developed a dependence on hydrocodone while prescribed to it turn to heroin as a substitute afterward.
Hydrocodone Abuse Statistics Prescription opioids such as hydrocodone are the fourth most common addiction in the U. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Precautions See also Warning section. Before taking this medication , tell your doctor or pharmacist if you are allergic to it; or to other opioids such as hydromorphone , morphine , codeine ; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: This drug may make you dizzy or drowsy.
Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
Liquid products may contain sugar and alcohol. Ask your doctor or pharmacist about using this product safely. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs , nonprescription drugs, and herbal products. During pregnancy , this medication should be used only when clearly needed.
It may harm an unborn baby. Discuss the risks and benefits with your doctor. This medication passes into breast milk and may rarely have undesirable effects on a nursing infant. Tell the doctor right away if your baby develops unusual sleepiness, difficulty feeding, or trouble breathing. Consult your doctor before breast -feeding.
Interactions See also Warning section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Pregnancy As with other NSAID-containing products, Vicoprofen should be avoided in late pregnancy because it may cause premature closure of the ductus arteriosus. Precautions General Vicoprofen cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of corticosteroids may lead to disease exacerbation. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.
The pharmacological activity of Vicoprofen in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions. Special Risk Patients As with any opioid analgesic agent, Vicoprofen tablets should be used with caution in elderly or debilitated patients, and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy or urethral stricture.
The usual precautions should be observed and the possibility of respiratory depression should be kept in mind. Cough Reflex Hydrocodone suppresses the cough reflex; as with opioids, caution should be exercised when Vicoprofen is used postoperatively and in patients with pulmonary disease.
These laboratory abnormalities may progress, may remain essentially unchanged, or may be transient with continued therapy. In addition, rare cases of severe hepatic reactions, including jaundice and fatal fulminant hepatitis, liver necrosis and hepatic failure, some of them with fatal outcomes have been reported. If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur e.
This may be due to fluid retention, occult or gross GI blood loss, or an incompletely described effect upon erythropoiesis. Patients on long-term treatment with NSAIDs including ibuprofen, should have their hemoglobin or hematocrit checked if they exhibit any signs or symptoms of anemia.
NSAIDs inhibit platelet aggregation and have been shown to prolong bleeding time in some patients. Unlike aspirin, their effect on platelet function is quantitatively less, of shorter duration, and reversible. Patients receiving Vicoprofen who may be adversely affected by alterations in platelet function, such as those with coagulation disorders or patients receiving anticoagulants, should be carefully monitored. Pre-existing Asthma Patients with asthma may have aspirin-sensitive asthma.
The use of aspirin in patients with aspirin-sensitive asthma has been associated with severe bronchospasm, which may be fatal. Since cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, Vicoprofen should not be administered to patients with this form of aspirin sensitivity and should be used with caution in patients with pre-existing asthma.
Aseptic Meningitis Aseptic meningitis with fever and coma has been observed on rare occasions in patients on ibuprofen therapy as found in Vicoprofen. Although it is probably more likely to occur in patients with systemic lupus erythematosus and related connective tissue diseases, it has been reported in patients who do not have an underlying chronic disease. If signs or symptoms of meningitis develop in a patient on Vicoprofen, the possibility of its being related to ibuprofen should be considered.
Information for Patients Patients should be informed of the following information before initiating therapy with an NSAID and periodically during the course of ongoing therapy. Alcohol and other CNS depressants may produce an additive CNS depression, when taken with this combination product, and should be avoided. Vicoprofen may be habit-forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, and no more frequently than prescribed.
Although serious CV events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and should ask for medical advice when observing any indicative sign or symptoms. Vicoprofen, like other NSAID-containing products, can cause GI discomfort and serious GI side effects, such as ulcers and bleeding, which may result in hospitalization and even death.
Although serious GI tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptoms including epigastric pain, dyspepsia, melena, and hematemesis.
Risk of Ulceration, Bleeding, and Perforation. Although serious skin reactions may occur without warning, patients should be alert for the signs and symptoms of skin rash and blisters, fever, or other signs of hypersensitivity such as itching, and should ask for medical advice when observing any indicative signs or symptoms.
Patients should be advised to stop the drug immediately if they develop any type of rash and contact their physicians as soon as possible. Patients should promptly report signs or symptoms of unexplained weight gain or edema to their physicians. Patients should be informed of the warning signs and symptoms of hepatotoxicity e. If these occur, patients should be instructed to stop therapy and seek immediate medical therapy.
Patients should be informed of the signs of an anaphylactoid reaction e. In late pregnancy, as with other NSAIDs, Vicoprofen should be avoided because it may cause premature closure of the ductus arteriosus.
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